Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck. The juvenile nasopharyngeal angiofibroma (JNA) is a highly Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male. Juvenile nasopharyngeal angiofibromas (JNA) are a rare benign but locally aggressive vascular tumor. Epidemiology Juvenile nasopharyngeal angiofibromas.

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All the 13 patients were males and no female case is reported in the present series. This may be attributed to a rich vasculature and lack of encapsulation. Four patients had conductive hearing loss because of serous otitis media caused by eustachian tube block. One patient with stage IIA disease case no. Patients tolerated nasal obstruction better than epistaxis. Fisch classification, however, is currently accepted. In these entire patients, ipsilateral maxillary artery was found to be the major feeding vessel.

Angiofibromas originating outside the nasopharynx may appear as an intraoral mass in the retromolar or buccal space area.

Prognosis for nasopharyngeal angiofibroma is favorable. Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma. You can also scroll through stacks with your mouse wheel or the keyboard arrow keys.

Type I includes lesions fundamentally localized to the nasal cavity, paranasal sinus, nasopharynx, or pterygopalatine fossa. Based on the clinical and radiological features, JNA is classified into three types. Angiofibroma, Nasopharynx, Neoplasm staging, Recurrence. Anterior bowing of the posterior maxillary wall, due to invasion of the pterygomaxillary space on axial CT, known as the Beliq sign is one of the characteristic findings.

Nasopharyngeal angiofibroma

The presentation is typically with obstructive symptoms, epistaxisand chronic otomastoiditis due to obstruction of the Eustachian tube. Blood vessels were seen in large number at the periphery of the lesion [ Figure 5 ].


However, this upstaging did not prevent total excision surgically with the approach that was planned prior to surgery. Nasopharyngeal angiofibroma also called juvenile nasopharyngeal angiofibroma [1] [2] is a histologically benign but locally aggressive vascular tumor that grows in the back of the nasal cavity.

This approach gave excellent visualization of entire nasopharynx, and gave good exposure of sphenoid sinus. Check for errors and try again. Diagnosis of JNA is made by complete history, clinical examination, radiography, nasal endoscopy; and specialized imaging techniques such as arteriography, CT, and magnetic resonance imaging MRI. On palpation, the swelling was firm and nontender. The blood vessels are slit-like or dilated, naaofaring in clusters and are of different calibers.

Nasopharyngeal angiofibroma – Wikipedia

Partial maxillectomy was done in ansofaring no 1 and 6. This benign hamartomatous lesion has great potential for growth in all directions, eroding bony confines.

The extent of JNA growth is studied clinically and radiologically by contrast enhanced computerized tomography CT scan nasofarint staged accordingly. They account for only 0.

Histopathology reveals a fibrocellular angiofibtoma with spindle cells and haphazard arrangement of collagen interspersed with an irregular vascular pattern. Case 2 Case 2. Clinically, however, it is obscure with painless, progressive unilateral nasal obstruction being the common presenting symptom with or without epistaxis and nasofxring. True maxillary sinus involvement was not seen in any patient but soft tissue density seen on CT scan in case nos.

The excised gross specimen was soft to firm in consistency, white to yellow with darker vascular areas.

Juvenile nasopharyngeal angiofibroma | Radiology Reference Article |

A history of head ache was given by 6 patients case nos. Thus, early diagnosis, accurate staging, and adequate treatment are essential in the management of this lesion.


The classification and clinical staging is relatively easy and helps to plan treatment and determine prognosis. Support Radiopaedia and see fewer ads. JNA is benign but locally destructive. Conclusion Juvenile nasopharyngeal angiofibroma or nasopharyngeal angiofibroma is an uncommon disease of male adolescents. JNA originating from area surrounding sphenopalatine foramen commonly presents with nasal obstruction and epistaxis.

Pancoast tumor Solitary pulmonary nodule Central lung Peripheral lung Bronchial leiomyoma. Articles from Journal of Oral and Maxillofacial Pathology: Plain radiographs no longer play a role in the workup of a suspected juvenile nasopharyngeal angiofibroma, however they may still be obtained in some instances during the assessment of nasal obstruction, or symptoms of sinus obstructions. Received Jul 15; Accepted Jun 1. Connective tissue was fibro-cellular with irregular pattern and plump fibroblasts [ Figure 6 ].

The condition is most commonly treated by surgical excision and the surgical approach is chosen according to the disease stage. Diagnosis is arrived at by clinical examination, radiography, nasal endoscopy and specialized imaging techniques such as CT scan and MRI.

It presents most commonly with nasal obstruction and intermittent moderate to severe nasal bleeding. However, most authors agree that JNAs arise from the posterior choanal tissues in the region of the sphenopalatine foramen. The propensity of the lesion to cause life threatening complications by way of massive bleeding has led to acquisition of considerable importance in otolaryngology practice.

Discussion All the 13 patients were males and no female case is reported in the present series.