The concept that the immune system can recognize and destroy nascent transformed cells was originally embodied in the cancer immunosurveillance. Request PDF on ResearchGate | Cancer Immunoediting: From Immunosurveillance to Tumor Escape | The concept that the immune system. Cancer Immunoediting from Immunosurveillance to Tumor Escape in Microvillus- Formed Niche: A Study of Syngeneic Orthotopic Rat Bladder.

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Cancer immunoediting: from immunosurveillance to tumor escape.

This hypothesis was abandoned shortly afterwards because of the absence of strong experimental evidence supporting the concept. New data, however, immunoedifing show the existence of cancer immunosurveillance and also indicate that it may function as a component of a more general process of cancer immunoediting. This paper has highly influenced 39 other papers.


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Topics Discussed in This Paper. Monitoring, Immunologic Immune system.

Citations Publications citing this paper. Showing of 1, extracted citations. Targeted therapeutic remodeling of the tumor microenvironment improves an HER-2 DNA vaccine and prevents recurrence in a murine breast cancer model. Reisfeld Cancer research Immunotherapy in head and neck cancer: Modeling putative therapeutic implications of exosome exchange between tumor and immune cells.

RNA pulsed dendritic cells: Lakshmi PrabhaRajeev K. Ultrastructural descriptions of heterotypic aggregation between eosinophils and tumor cells in human gastric carcinomas. Understanding tumor heterogeneity as functional compartments – superorganisms revisited Thomas G.

Burdach Journal of Translational Medicine Vaccine prevention of cancer: WeinerRishi SuranaJoseph C. Murray Cancer fron research Abdel-MotalKim M.

References Publications referenced by this paper. Showing of references. Aids-related malignancies Chris H. Valiante The Journal of experimental medicine Effect of neonatal thymectomy on tymor induction of sarcomata.


Cancer immunoediting: from immunosurveillance to tumor escape

RussellTimothy J. Ley Annual review of immunology Spinning molecular immunology into successful immunotherapy. Drew Mark Pardoll Nature reviews. Street immunoeditinv, Joseph A. By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy PolicyTerms of Serviceand Dataset License.