Noma is an opportunistic infection promoted by extreme poverty. It evolves rapidly from a gingival inflammation to grotesque orofacial gangrene. Cancrum oris. Prevalence: Unknown; Inheritance: ; Age of onset: Childhood; ICD A; OMIM: ; UMLS: C; MeSH: D; GARD: Cancrum oris or noma (from the Greek nomein, “to devour”)1 is a “gangrenous affection of the mouth, especially attacking children in whom the constitution is.

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As most patients with noma do not report until the disease is at an advanced stage, its onset and progression still remains a mystery. By using this site, you agree to the Terms of Use and Privacy Policy. Delayed treatment will not allow a return to status quo ante.

Noma (disease)

The risk factors associated with noma are malnutrition, intercurrent disease such as rubella or malaria, poor oral hygiene, and the presence of a lesion of the gingival mucosa an early sign of necrotising gingivitis.

Am J Trop Med Hyg ; Fusobacterium necrophorum and Prevotella intermedia are important bacterial pathogens in this disease process, interacting with one or more other bacterial organisms such as Borrelia vincentiiPorphyromonas gingivalisTannerella forsythiaTreponema denticolaStaphylococcus aureusand certain species of nonhemolytic Streptococcus. Chlamydia trachomatis Chlamydia Cancru venereum Trachoma. How to cite this article: Survivors of this disease suffer severe facial deformity due ooris loss of facial tissues and scarring.

Often they have had an illness such as measles, scarlet fever, tuberculosis, or cancer. None, Conflict of Interest: The documents contained in this web site are presented for information purposes only. Other times, the condition may heal over time even without treatment.


In some cases, this condition can be deadly if it is not treated. Teeth pulpdentinenamel. Plastic surgery may be necessary to remove destroyed tissues and reconstruct facial bones. The destruction of the bones around the mouth causes deformity of the face and loss of teeth. Management and treatment The management of acute noma is aimed at improving the health status introduction of a balanced diet cancurm vitamin supplements, and sufficient hydration of affected individuals and providing topical care.

There may be other signs of malnutrition. Teams of cancrkm medics coming from abroad are often needed to support the local capacity to address the most severe cases, which can be extremely challenging even for senior maxillofacial surgeons. This will improve facial appearance and the function of the mouth and jaw. Nasopalatine duct Median mandibular Median palatal Traumatic bone Osteoma Osteomyelitis Osteonecrosis Bisphosphonate-associated Neuralgia-inducing cavitational osteonecrosis Osteoradionecrosis Osteoporotic bone marrow defect Paget’s disease of bone Periapical abscess Phoenix abscess Periapical periodontitis Stafne defect Torus mandibularis.

Sushil Subedi, Oral and Maxillofacial surgeon and the head of Department. It is often reported as a oriz to acute necrotising ulcerative gingivitis.

Noma: MedlinePlus Medical Encyclopedia

Confounding interactions of malnutrition with infection. Its exact prevalence is unknown. Squamous cell papilloma Keratoacanthoma Malignant: Hope for Africa’s Hidden Children”.

The disease is associated with high morbidity and mortality [8] and affects mainly children in the poorest cancdum of Africa. The management of acute noma is aimed at improving the health status introduction of a balanced diet and vitamin supplements, and sufficient hydration of affected individuals and orus topical care.


The disease develops very rapidly and in isolated regions medical care is often only sought after the lesions are well established.

The dehumanizing oro-facial gangrenous lesion affects predominantly children ages 2 to 16 years, particularly in sub-Saharan Africa, where the estimated frequency in some communities varies from 1 to 7 cases per population. Infectious diseases Bacterial diseases: Chlamydophila psittaci Psittacosis Chlamydophila pneumoniae.

Oro-facial gangrene (noma/cancrum oris): pathogenetic mechanisms.

Post-operative photograph after reconstruction Click here to view. In other projects Wikimedia Commons. Disorders of the Mucous membranes.

Other Eagle syndrome Hemifacial hypertrophy Facial hemiatrophy Oral manifestations of systemic disease. Periodontium gingivaperiodontal ligamentcementumalveolus — Gums and tooth-supporting structures.

Related articles Cancrum oris gangrenous stomatitis noma. Other search option s Alphabetical list. However, it can cause severe scarring and deformity. cancrrum

The versatility of pectoralis major and latissimus dorsi myocutaneous flaps in the reconstruction of cancrum oris defects of children and adolescents. Orofacial soft tissues — Soft tissues around the mouth. How to cite this URL: