Oral Surg Oral Med Oral Pathol. Sep;60(3) Lichenoid dysplasia: a distinct histopathologic entity. Krutchkoff DJ, Eisenberg E. We have observed. Citation. M Virdi, A Sachdev, A Gupta, K Aggarwal. Lichen Planus Or Lichenoid Dysplasia: Is It Premalignant!. The Internet Journal of Head and Neck Surgery. We have observed, both in the literature and in practice, that pathologists frequently fail to appreciate subtle dysplastic features in lesions with lichenoid.

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According to them, many of the cases that eventually evolved to epidermoid carcinoma were actually lichenoid dysplasia cases wrongly diagnosed as lichen planus, given the large number of histopathologic similarities between both lichsnoid, more specifically when in their early stages.

Lichenoid Dysplasia–A Case Report with a Review of Differential Diagnosis

Drug related LL is considered as a different form of delayed hypersensitivity reaction, wherein drug or its metabolite acts as haptens. Krutchkoff DJ, Eisenberg E. Thus these parameters may used to predict their behavior.

Unfolded cells with clear outline were only selected for the study. Some cell alterations which suggest malignancy present in the oral lichen planus may also be found in epithelial dysplasia, impairing its diagnosis and, consequently, stressing the importance of following these patients in the long run.

Current controversies in oral lichen planus: Gingival involvement of oral lichen planus in a series of patients. Doubtful cases were immediately discarded and replaced.

Lichenoid dysplasia: a distinct histopathologic entity.

Rajendran R, Sivapathasundharam B. Objectives of the study Measurement and Comparison of nuclear and cytoplasmic volume of basal cells in OLP, normal mucosa, and oral carcinoma. Moreover morphometric studies may help to distinguish benign from potentially premalignant lichen planus 7.

Confounding factors such as smoking were taken into consideration while diagnosing 8.

Lichenoid Dysplasia–A Case Report with a Review of Differential Diagnosis

However, in view of both the common occurrences of OLP and unresolved issues regarding its premalignant potential, the need for close follow-up of lesions with clinical lichenoid features clearly is illustrated 2.

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Clinico-pathological mimicry and its diagnostic implications. Br Dent J ; Reaching a diagnosis lichwnoid oral lichen planus is no easy task due to the lack of accurate clinical and histopathologic criteria. Oral lichenoid lesions- a review and update. Thus the parameters studied may have a value in predicting their behavior. Dyxplasia the present study enlargement of cell dimension is noticed in basal as well as spinous layer.

Pathology and genetics head and neck tumours.

According to these authors, the cases of development to malignancy described in the literature are related to a condition with distinct histopathologic characteristics known as lichenoid dysplasia.

Case report and review of literature.

Spinous cell maximum diameter has also increased from normal mucosa to OLP to oral sq cell carcinoma. Eisenberg E, Krutchkoff DJ. Articles from Journal of Clinical and Diagnostic Research: Progress in understanding its malignant potential and the implications for clinical management. It can be concluded from this study that the accuracy and objectivity of morphometric methods may be applied usefully to discriminate between purely benign, potentially premalignant dyplasia malignant lesions of the oral cavity.

Quantitative cytology can detect both cytoplasmic and nuclear changes in oral lichen- planus, suggests that this technique may be of potential value for the repeated assessment of dysplastic changes within oral lichen planus lesions 5.

Mucosal erythema of obscure origin displaying spontaneous, usually temporary, partial to complete regression may be common to both purely inflammatory conditions like lichen planus and early epithelial dysplasia. Open in a separate window.

Although it has lichehoid confirmed that these two entities are entirely different with not so similar etiopathogenesis, yet the confusion still exists. While some experts believe in an innate malignant capacity for OLP, others claim that only OLP-like xysplasia with dysplasia— referred to as lichenoid dysplasia, or LD—are potentially cancerous. The chi-squared test did not show statistically significant differences between oral lichen planus and epithelial dysplasia in relation to the following cell alterations: The oral lesions of Lichen planus.


Indeed, the possibility of evolving malignantly reflects a series of cell-intrinsic molecular alterations seen in lichenoid dysplasia 21as reported by Kim et al. Repeated biopsies to be done when recurrence, change or spread is detected. Find articles by Mihir Jha.

Cancer and oral lichen planus in llchenoid Swedish population. Although the incidence of LD is far less than lichen planus, but when present its distinction from the latter is often difficult. The possible pre malignant character dysplsia oral lichen planus and oral lichenoid lesions: Nuclear and cellular volumes may serve as potential discriminators between benign lesions and premalignant lichen planus. In addition lidhenoid these four categories, Kumar S et al.

The lesion had irregular margins with slightly raised surface and measured around 1. Photomicrograph revealing hyperparakeratinized hyperplastic epithelium with saw tooth shaped rete ridges black arrows and juxta epithelial band of chronic inflammatory cells blue arrow H and E, 40X. The literature discussed in the article is an attempt to segregate individual lichenoid lesions by defining clinical and histopathologic variations among each other, which avoids the diagnostic problem.

Lichenoid lesions of oral mucosa. Cytomorphometric analysis of exfoliated dysplasa buccal mucosa cells. Statistically significant differences were noted and the results obtained may have a value in predicting their behavior.

Only one patient used tobacco cigarettes –this patient had recurrent oral candidiasis and was receiving multiple medications.

J Oral Maxillofacial Surg ; Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications.